Ultrastructural studies of the liver in acute and chronic ethionine intoxication.
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Ultrastructural studies of the liver in acute and chronic ethionine intoxication.

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Published in [Toronto] .
Written in English


  • Ethionine,
  • Liver

Book details:

Edition Notes

ContributionsToronto, Ont. University.
The Physical Object
Paginationiv, 433 leaves.
Number of Pages433
ID Numbers
Open LibraryOL20794683M

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Ultrastructural, immunohistochemical and biochemical investigations of the rat liver exposed to experimental diabetes und acute hypoxia with and without application of Ginkgo extract. Welt K(1), Weiss J, Martin R, Dettmer D, Hermsdorf T, Asayama K, Meister S, Fitzl by: Drugs represent useful tools in the study of various cellular metabolic pathways and it is of interest to analyze the early stages of drug-induced response of the liver to chemical injury. Too often in the past the ultrastructural studies have led to an accumulation of data, often purely anecdotal, and to a dispersion of the by: 6. Ethionine was given in acute experiments to 6 dogs and in chronic experi­ ments to 42 dogs, 5 cats and 2 monkeys. The dosage and route of administra­ tion are given in the section on Experiments and Results. Acute studies of pancreatic secretion. In . Similar changes Morphologic Studies of Alcoholic Liver Injury have been shown in the liver of amyloidosis [,]. When collagen is degraded, the associated GAG also disappears. In this respect, a hepatic enzyme that degrades highly polymerized hyaluronic acid and other GAG has been localized in hepatic lysosomes[97].Cited by: 2.

  Acute liver failure (ALF) is a clinical syndrome resulting from massive necrosis of hepatocytes or from severe functional impairment of hepatocytes. Leading cause in developing countries is viral hepatitis, autoimmune diseases, where as in developed countries, drugs mainly acetaminophen is the most common cause of acute liver failure. N-Acetyl Cysteine, a Author: Shikha Handa, Jyoti Walia, B.P Kalra. The significance of chronic heart disease, fatty liver, and consumption of barbiturate and librium on a tolerance to ethyl alcohol, as judged in a postmortem Cited by: liver disease. Usually inflammation is associated with steatohepatitis, however our results demonstrate that chronic ethanol exposure increased the expression of the inflammatory gene interleukin-1b. Paradoxically the expression of adiponectin receptor-2 and sirtuin-1 also increased for attenuating the liver injury. Ultrastructural. Chronic alcohol intoxication induces hepatic injury through enhanced macrophage inflammatory protein‐2 production and intercellular adhesion molecule‐1 expression in the liver A P Bautista Department of Physiology, Louisiana State University Medical Center, New Orleans , USACited by:

Electron microscopic studies were made on liver biopsy specimens from 18 patients with alcoholic liver disease. Alterations of mitochondria, microbodies, lysosomes and endoplasmic reticulum were more frequent and more severe than in normal volunteers given alcohol. Abnormalities of the mitochondrial membranes, the presence of alcohol hyaline and the leucocytic and Cited by: No differences were noted between the liver lipides of animals that were fed until the first injection and those of rats previously fasted.. Compounds-We are indebted to U. S. Industrial Chemicals, Inc., for the nL-ethionine used in these studies. The L-ethionine was prepared from. A significant liver damage occurred following an acute and a hyper-acute Zn 3 P 2 toxicity with more deleterious effects in the hyper-acute toxicity, indicating a dose dependent hepatic damage. This test may be performed to assess liver function, and/or to evaluate treatment of acute liver disease, such as hepatitis. Aspartate transaminase (AST) test: This test measures the level of aspartate transaminase (an enzyme that is found in the liver, kidneys, pancreas, heart, skeletal muscle, and red blood cells) that is released into the.